Energy Balance: The Simple Principle of Weight Loss | Using Strategies to Get Started | Looking at Weight Loss Aids | Setting Realistic Goals

Related Media: Changing Our Eating Habits

image for weight loss option article The prevalence of obesity has increased steadily in Western cultures over the past century, particularly during the last several decades. In fact, most health professionals agree that we are in the midst of an obesity epidemic in the United States.

Being overweight is closely linked to many very serious health conditions, most particularly risk factors for heart disease and stroke, including high blood pressure, high cholesterol, high triglycerides, low levels of HDL (high-density lipoprotein—the "good" cholesterol), and type 2 diabetes. Fortunately, even modest reductions in weight can help improve these conditions. Plus, practicing the behavioral changes of a healthier diet and regular exercise can actually reduce these risk factors whether weight loss occurs or not.

Looking at Weight Loss Aids

There is a great deal of interest in whether prescription medicines or supplements can facilitate weight loss. Some medicines suppress appetite by interfering with brain chemicals that affect mood and appetite. Others reduce fat absorption from the gut. Here are examples of medicines that may be recommended for weight loss:

  • Diethylpropion (eg, Tenuate, Tenuate Dospan)
  • Orlistat (eg, Alli [nonprescription], Xenical [prescription])
  • Phendimetrazine (eg, Bontril)
  • Phentermine (eg, Adipex-P)

Some studies have supported the use of these medicines when combined with lifestyle changes. For example, as part of a review of weight loss drugs, researchers analyzed 15 trials involving almost 10,000 people who were either taking orlistat or placebo. Compared to the placebo group, those taking orlistat had a higher chance of achieving a 5% or 10% weight loss. These types of medicines, though, are usually prescribed only for people who are severely obese when other methods of weight loss have not worked. Accordingly, these medicines are not without side effects or potential adverse events and should only be used with careful monitoring by your doctor.

The same goes for dietary supplements. Supplements do not undergo the same rigorous approval process as drugs. That being said, certain supplements may provide weight loss benefits since they may contain similar mechanisms of action as drugs. Along the same line, some of the same risks and side effects may be present, as well, which is why you should talk to your doctor before taking any over-the-counter weight loss products.

Also, be sure you know what is in diet medicines and supplements. Some medicines and supplements that were used in the past have been pulled from the market as it was found that the dangers of taking them were higher than the benefits. Whenever you are considering taking a diet supplement, know exactly what is in the product and share this information with your doctor.

The question is: when should you consider taking these weight loss aids? While it depends on your overall health and medical history, the best approach may be a conservative one. For example, adopt lifestyle changes for 6-12 months before trying a drug or supplement. Your doctor can give you guidance as to which weight loss options you should try first.