Definition | Reasons for Procedure | Possible Complications | What to Expect | Call Your Doctor

Reasons for Procedure

You may need to be treated by having a splenectomy if you have:

  • Trauma to the spleen
  • Spleen rupture due to tumor, infection, inflammatory condition, or medicines
  • Enlargement of the spleen (splenomegaly)
  • Certain blood disorders
  • Myelofibrosis (abnormal formation of fibrous tissue in the bone marrow)
  • Damage in the blood vessels of the spleen
  • Leukemia or lymphoma
  • Diseased spleen, due to disorders like HIV infection
  • Tumor or abscess in the spleen
  • Liver disease

Possible Complications

If you are planning to have a splenectomy, your doctor will review a list of possible complications, which may include:

Factors that may increase the risk of complications include:

  • Obesity
  • Smoking
  • Poor nutrition
  • Recent or chronic illness
  • Diabetes
  • Old age
  • Heart or lung disease
  • Bleeding or clotting disorders

What to Expect

Your doctor may do the following:

  • Physical exam
  • Blood and urine tests
  • Review of medicines
  • X-rays of abdomen—a test that uses radiation to take a picture of structures inside the body
  • CT scan—a type of x-ray that uses a computer to make pictures of the inside of the body
  • Ultrasound—a test that uses sound waves to visualize the inside of the body
  • Electrocardiogram (ECG, EKG)—a test that records the heart's activity by measuring electrical currents through the heart muscle
  • Other tests to evaluate spleen enlargement
  • Studies to determine rate of destruction of red blood cells and/or platelets
  • Give you vaccines against some infections (Without your spleen, you will be more susceptible to certain infections.)

Talk to your doctor about your medicines. You may be asked to stop taking some medicines up to one week before the procedure, like:

  • Aspirin or other anti-inflammatory drugs
  • Blood thinners, such as clopidogrel (Plavix) or warfarin (Coumadin)

General anesthesia will be used. You will be asleep.