Function | Recommended Intake | Thiamin Deficiency | Thiamin Toxicity | Major Food Sources | Health Implications | Tips for Increasing Your Thiamin Intake:

image Thiamine, also called vitamin B1, is a water-soluble vitamin found in virtually every cell in the body. Water-soluble vitamins are stored in the body in very limited amounts and are excreted through the urine. For this reason, it is a good idea to have them in your daily diet. Thiamine is also available as a supplement and by prescription as an injection.

Health Implications

A severe thiamine deficiency, though rare in the US, can cause the disease beriberi. Beriberi can damage the heart and the nervous system. Symptoms include fatigue, diarrhea, weight loss, memory loss, and heart failure. This condition is still seen in people who abuse alcohol, in people whose ability to absorb thiamine is impaired, and in developing countries where foods are not fortified. Treating beriberi with vitamin B1 cures most cases, though severe deficiency can cause irreversible damage.

A deficiency of thiamine can cause Korsakoff’s Syndrome, which mainly affects short-term memory. Symptoms of Korsakoff’s syndrome include difficulty with walking and balance, paralysis of some of the eye muscles, confusion, and drowsiness. It is often caused by alcoholism and also occurs with forms of brain damage, such as tumors, head injuries, and strokes. Treatment of Korsakoff’s syndrome involves intravenous thiamine and oral thiamine supplements over many months. If alcoholism is the cause, that also needs to be treated.

In people with congestive heart failure (CHF), the heart's ability to pump weakens, and fluid begins to accumulate in the lungs and legs. Loop diuretics are often prescribed to treat CHF. However, these drugs can deplete the body of thiamine. Since thiamine is required for normal heart function, this can cause problems. Thiamine supplements may be prescribed in these cases.