About the Study | How Does This Affect You?

Obesity and being overweight are leading health concerns in the US. Being overweight is considered a risk for chronic diseases such as high blood pressure, heart disease, and diabetes. The general principle of weight loss is to use more calories than one consumes. This means lowering the amount of food eaten and increasing physical activity. However, many still struggle to achieve their weight loss goals. Some believe that the proportions of proteins, carbohydrates, and fats are a key factor to weight loss. This has resulted in a variety of specialized diets that over or under emphasizes a particular nutrient.

The Harvard School of Public Health wanted to clarify what type of nutrient change if any was best in reaching weight loss goals. The study published in the New England Journal of Medicine found no significant difference in weight loss between the diets.

About the Study

The randomized trial followed 811 participants over a two-year period. The participants were all offered group and individual instructional sessions over the study period. Changes were measured by body weight every six months. The participants were split into four groups. Each group was assigned a diet that emphasized carbohydrates, protein, or fat. The diet options were:

  • 20% of calories from fat, 15% from protein, and 65% from carbohydrates
  • 20% from fat, 25% from protein, and 55% from carbohydrates
  • 40% from fat, 15% from protein, and 45% from carbohydrates
  • 40% from fat, 25% from protein, and 35% from carbohydrates

The goal in all four groups was to reduce their caloric intake by 750 calories per day. Researchers recorded weight loss and dietary changes. At the end of the program, on average, all groups lost the same amount of weight. The researchers noted that participants that attended support sessions lost more weight than those that did not attend.

There are some concerns with this study. There was a high dropout rate with only 79.5% of the participants completing the study. The participants also had difficulty adhering to the dietary guidelines that were established. Few reached their dietary goals.